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1. You measure the following data for the 1:1 binding of a fluorescent drug to a cancer-causing kinase.
Estimate the Ka value of the drug-kinase complex. [drug] A fluorescence 10-1′ M 0.015 10-10 M 0.136 10-9
M 0.750 108 M 1.364 10-7 M 1.485 10-6 M 1.498 10-5 M 1.499 2. HPW defines a domain as s