A 32-year-old woman presents with complaints of “drooping…
by | Mar 29, 2024 | Uncategorized
- A 32-year-old woman presents with complaints of “drooping eyelids,” difficulty chewing and swallowing, and weakness of her arms and legs that is less severe in the morning but becomes worse as the day progresses. She complains that climbing stairs and lifting objects are becoming increasingly difficult. Clinical examination confirms weakness of the eyelid and jaw muscles. She is told that she may have myasthenia gravis and is scheduled for testing using the short-acting acetylcholinesterase inhibitor edrophonium (Tensilon).
- Explain the pathogenesis of this woman’s symptoms as it relates to myasthenia gravis.
- Explain how information from the Tensilon administration can be used to assist in the diagnosis of the disorder.
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