Question
This 20-year-old female came to the outpatient procedure area with a diagnosis of anemia. A bone marrow aspiration was performed in the following manner. Manubrial area was prepped with Betadine. Skin and periosteum anesthetized with 2 percent Xylocaine. Skin incision was made with #11 Bard Parker blade, and marrow aspirations performed with U of IL sternal needle. Patient tolerated the procedure with no complaints or complications. Advised to resume normal activity. Diagnosis: Iron deficiency anemia Pathology Report Specimen Received: Bone marrow aspiration and biopsy
Question
This 20-year-old female came to the outpatient procedure area with a diagnosis of anemia. A bone marrow aspiration was performed in the following manner. Manubrial area was prepped with Betadine. Skin and periosteum anesthetized with 2 percent Xylocaine. Skin incision was made with #11 Bard Parker blade, and marrow aspirations performed with U of IL sternal needle. Patient tolerated the procedure with no complaints or complications. Advised to resume normal activity. Diagnosis: Iron deficiency anemia Pathology Report Specimen Received: Bone marrow aspiration and biopsy Pathologic Diagnosis: Slightly hypercellular marrow with diminished iron consistent with iron deficiency anemia Microscopic Description: The bone marrow specimen is adequate. The marrow appears to be slightly hypercellular with a cell-to-fat ratio of 60/40. Megakaryocytes are easily found. Most of them are of normal morphology. There is nothing to suggest a primary or metastatic neoplastic proliferation. Granuloma is not found. The maturation of myeloid cells is complete. A Prussian blue stain obtained on both specimens shows diminished stainable iron. The specimen appears to be marrow aspiration. Bone trabecula are not seen in any of it. A reticulin stain was obtained. There is no evidence of significant increase in reticulin in the marrow stroma. The marrow smears show adequate number of spicules. The complete maturation of myeloid cells is confirmed. Hemoglobinization of erythroid cells is slightly deficient. There is no evidence of excessive number of blasts. The myeloid/erythroid ratio is within normal limits. Plasma cells amount to less than 1 percent of the cells counted. A review of the peripheral blood smear received shows no abnormal morphological changes in any of the cell lines.
